Phyllodes Tumor of the Breast: a Clinicopathological Analysis from a Single Institution

The aim of our study is to examine the clinical and pathological features of patients with breast phyllodes tumors and to determine features that are correlated with outcome. Forty-four phyllodes tumors were assessed. There were 11 benign, 11 borderline and 22 malignant tumors. Ten of 44 patients (22.72%) relapsed at any site. Seven patients (15.9%) had a local recurrence (LR), and three patients experienced a local and metastatic relapse. The 5-year and 10-year survival rates are 97% and 95% respectively. The five years and ten years disease free survival (DFS) are 81% and 77% respectively. Grade, histological size, margin involvement impacted disease free survival. Adjuvant radiation therapy improved local control in high-grade tumors although it did not reach significance.